Institut National de la Recherche Agronomique
#2 - Unité de Virologie Immunologie Moléculaires (VIM)
Contact
Team Leader: Dr. Hubert Laude
U892 Virologie Immunologie Moléculaires - Domaine de Vilvert
Jouy en Josas, 78350, France
Contact: Dr. Hubert Laude
Tel: +33 (0) 1 34 65 26 00
Fax: +33 (0) 1 34 65 26 21
E-mail: hubert.laude@jouy.inra.fr
Institute website:
http://www.jouy.inra.fr/anglais/index-en.shtml
Main area of research
- Prion biology in cell culture models
- Prion diversity in transgenic mousemodels
- Prion strains and species barrier
Research Team
- Researchers: 3
- Technicians: 3
- Postdocs: 1
- PhD/MD Students: 2
Facilities and Equipment
- Laboratories: BSL1, BSL2, BSL3
- General equiment: Microbiology, Cell Biology, Cell culture, Neurobiology, Immunology, Biochemistry, Molecular biology, Biophysics
Main references
- Béringue V, Le Dur A, Tixador P, Reine F, Lepourry L, Perret-Liaudet A, Haïk S, Vilotte JL, Fontés M & Laude H. (2008). Prominent and Persistent Extraneural Infection in Human PrP Transgenic Mice Infected with Variant CJD. PLoS ONE 3, e1419.
- Cronier S, Beringue V, Bellon A, Peyrin JM & Laude H. (2007). Prion strain- and species-dependent effects of antiprion molecules in primary neuronal cultures. J Virol. 81, 13794-800.
- Béringue V, Andréoletti O, Le Dur A, Essalmani R, Vilotte JL, Lacroux C, Reine F, Herzog L, Biacabé AG, Baron T, Caramelli M, Casalone C & Laude H.( 2007). A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission. J Neurosci. 27, 6965-71.
- Beringue V, Bencsik A, Le Dur A, Reine F, Lai TL, Chenais N, Tilly G, Biacabe AG, Baron T, Vilotte JL & Laude H. (2006). Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy. PLoS Pathog. 2, e112.
- Le Dur A, Beringue V, Andreoletti O, Reine F, Lai TL, Baron T, Bratberg B, Vilotte JL, Sarradin P, Benestad SL & Laude H. (2005). A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A. 102, 16031-6.
