University of Edinburgh
#7 - National CJD Surveillance Unit
Contact
Team Leader: Prof. Robert Will
Western General Hospital
Edinburgh, EH4 2XU, United Kingdom
Contact: Prof. Robert Will
Tel: +44 (0)131 537 2128
Fax: +44 (0)131 343 1404
E-mail: r.g.will@ed.ac.uk
Institute website:
www.ed.ac.uk
Main area of research
- Epidemiology and clinical features of human prion diseases
- Development and assessment of diagnostic test in CJD
- Risk assessment in CJD
Research Team
- Researchers: 6
- Technicians: 1
- Postdocs: -
- PhD/MD Students: 2
Facilities and Equipment
- Laboratories: BSL2, BSL3
- General equipment: Pathology, Biochemistry, Molecular biology, Histology, Imaging, Epidemiology, Risk assessment
- Special equipment: Automated sequencer
- Specific methods: Analysis of CSF proteins
Main references
- Will,R.G., Ironside,J.W., Zeidler,M., Cousens,S.N., Estibeiro,K., Alperovitch,A., Poser,S., Pocchiari,M., Hofman,A., and Smith,P.G. (1996) A new variant of Creutzfeldt-Jakob disease in the UK. Lancet, 347,921-925.
- Llewelyn,C.A., Hewitt,P.A., Knight,R.S.G., Amar,K., Cousens,S., Mackenzie,J., and Will,R.G. (2004) Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet, 363,417-421.
- Pocchiari,M., Puopolo,M., Croes,E.A., Budka,H., Gelpi,E., Collins,S., Lewis,V., Sutcliffe,T., Giulivi,A., Delasnerie-Laupretre,N., Brandel,J.-P., Alperovitch,A., Zerr,I., Poser,S., Kretzschmar,H.A., Ladogana,A., Rietvald,I., Mitrova,E., Martinez-Martin,P., de Pedro Cuesta,J., Glatzel,M., Aguzzi,A., Cooper,S., Mackenzie,J., van Duijn,C.M., and Will,R.G. (2004) Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Brain, 127,2348-2359.
- Ladogana,A., Puopolo,M., Croes,E.A., Budka,H., Jarius,C., Collins,S., Klug,G.M., Sutcliffe,T., Giulivi,A., Alperovitch,A., Delasnerie-Laupretre,N., Brandel,J.-P., Poser,S., Kretzschmar,H., Rietvald,I., Mitrova,E., de Pedro Cuesta,J., Martinez-Martin,P., Glatzel,M., Aguzzi,A., Knight,R., Ward,H., Pocchiari,M., van Duijn,C.M., Will,R.G., and Zerr,I. (2005) Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada. Neurology, 64,1586-1591.
- Ward,H.J.T., Everington,D., Cousens,S.N., Smith-Bathgate,B., Leitch,M., Cooper,S., Heath,C., Knight,R.S.G., and Will,R.G. (2006) Risk factors for variant Creutzfeldt-Jakob disease: a case-control study. Ann Neurol, 59,111-120.
