National University of Ireland, Dublin
#11
Contact
Team Leader: Dr. Mark Rogers
Belfield
Dublin 4, , Ireland
Contact: Dr. Mark Rogers
Tel: +35 317162197
Fax: +35 317161152
E-mail: mark.rogers@ucd.ie
Institute website:
http://www.ucd.ie/
Main area of research
- Development of Novel methods for assessing infection in cell culture
- Assessing potential targets for therapy
Research Team
- Researchers: 3
- Technicians: 1
- Postdocs: 0
- PhD/MD Students: 2
Facilities and Equipment
- Laboratories: BSL1, BSL2
- General equipment: Cell Biology, Cell culture, Molecular biology, Imaging
- Special equipment: Wallac 1420 Multilabel reader
- Specific methods: Modified Scrapie Cell assay, Flow Cytometry assay
Main references
- Espinosa, J.C., Morales, M., Castilla, J., Rogers, M.S. and Torres, J.M. (2007) Progression of prion infectivity in asymptomatic cattle after oral BSE challenge. J Gen Micro 88:1379-83.
- Bandyopadhyay, S., Ni, J., Ruggiero, A., Walshe, K., Rogers, M.S., Naibedya Chattopadhyay, N.,Marcie A. Glicksman, M.A. and Rogers J.T.(2006) A High-Throughput Drug Screen Targeted to the 5’Untranslated Region of Alzheimer Amyloid Precursor Protein mRNA. J Biomol Screen 11:469-480
- Castilla, J., Gutiérrez-Adán, A., Brun, A., Doyle, D., Pintado, B., Ramírez, M. A., Salguero, F. J., Parra, B., San Segundo, F. D., Sánchez-Vizcaíno, J. M., Rogers, M., and Torres, J.M. (2004) Detection of subclinical BSE infection in transgenic mice expressing procine PrPC. Journal of Neuroscience 24:5063-5069.
- Rogers, M., Yehiely, F., Scott, M., and Prusiner, S. B. (1993) Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells. Proceedings of the National Academy Sciences U S A 90:3182-3186.
- Rogers, M., Serban, D., Gyuris, T., Scott, M., Torchia, T., and Prusiner, S. B. (1991) Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system. Journal of Immunology 147:3568-3574.
