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National University of Ireland, Dublin

National University of Ireland, Dublin

#11

Dr. Mark Rogers

Contact

Team Leader: Dr. Mark Rogers
Belfield
Dublin 4, , Ireland
Contact: Dr. Mark Rogers
Tel: +35 317162197
Fax: +35 317161152
E-mail: mark.rogers@ucd.ie
Institute website: http://www.ucd.ie/

Main area of research

  • Development of Novel methods for assessing infection in cell culture
  • Assessing potential targets for therapy

Research Team

  • Researchers: 3
  • Technicians: 1
  • Postdocs: 0
  • PhD/MD Students: 2

Facilities and Equipment

  • Laboratories: BSL1, BSL2
  • General equipment: Cell Biology, Cell culture, Molecular biology, Imaging
  • Special equipment: Wallac 1420 Multilabel reader
  • Specific methods: Modified Scrapie Cell assay, Flow Cytometry assay

Main references

  • Espinosa, J.C., Morales, M., Castilla, J., Rogers, M.S. and Torres, J.M. (2007) Progression of prion infectivity in asymptomatic cattle after oral BSE challenge. J Gen Micro 88:1379-83.
  • Bandyopadhyay, S., Ni, J., Ruggiero, A., Walshe, K., Rogers, M.S., Naibedya Chattopadhyay, N.,Marcie A. Glicksman, M.A. and Rogers J.T.(2006) A High-Throughput Drug Screen Targeted to the 5’Untranslated Region of Alzheimer Amyloid Precursor Protein mRNA. J Biomol Screen 11:469-480
  • Castilla, J., Gutiérrez-Adán, A., Brun, A., Doyle, D., Pintado, B., Ramírez, M. A., Salguero, F. J., Parra, B., San Segundo, F. D., Sánchez-Vizcaíno, J. M., Rogers, M., and Torres, J.M. (2004) Detection of subclinical BSE infection in transgenic mice expressing procine PrPC. Journal of Neuroscience 24:5063-5069.
  • Rogers, M., Yehiely, F., Scott, M., and Prusiner, S. B. (1993) Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells. Proceedings of the National Academy Sciences U S A 90:3182-3186.
  • Rogers, M., Serban, D., Gyuris, T., Scott, M., Torchia, T., and Prusiner, S. B. (1991) Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system. Journal of Immunology 147:3568-3574.

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