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Istituto Superiore di Sanita

Istituto Superiore di Sanita

#18 - Section of Persistent and slow Virus Infections, Laboratory of Virology

Prof. Maurizio Pocchiari

Contact

Team Leader: Prof. Maurizio Pocchiari
Viale Regina Elena 299
Roma, 00161, Italy
Contact: Prof. Maurizio Pocchiari
Tel: +39 (0) 6 4990 3203
Fax: +39 (0) 6 4990 3085
E-mail: maurizio.pocchiari@iss.it
Institute website: http://www.iss.it/chis/?lang=2

Main area of research

  • Surveillance of CJD
  • Diagnostic markers
  • Inactivation/Decontamination

Research Team Picture

Research Team

  • Researchers: 9
  • Technicians: 8
  • Postdocs: 2
  • PhD/MD Students: 3

Facilities and Equipment

  • Laboratories: BSL1, BSL2, BSL3
  • General equipment: Cell Biology, Cell culture, Pathology, Biochemistry, Molecular biology, Biophysics, Histology, Epidemiology, Risk assessment
  • Special equipment: Automated PMCA processor; Mass spectrometer; 2D electrophoresis system
  • Specific methods: Quantitative determination of pathological PrP allotypes; Differential 2D electrophoresis (in preparation); Real Time Immuno PCR (in preparation)

Main references

  • Capellari, S., Parchi, P., Cortelli, P., Avoni, P., Casadei, G.P., Bini, C., Baruzzi, A., Lugaresi, E., Pocchiari, M., Gambetti, P. & Montagna, P. (2008). Sporadic fatal insomnia in a fatal familial insomnia pedigree. Neurology 70, 884-885.
  • Berardi, V.A., Cardone, F., Valanzano, A., Lu, M., Pocchiari, M. (2006). Preparation of soluble infectious samples from scrapie-infected brain: a new tool to study the clearance of transmissible spongiform encephalopathy agents during plasma fractionation. Transfusion, 46, 652-658.
  • Nonno, R., Di Bari, M.A., Cardone, F., Vaccari, G., Fazzi, P., Dell’Omo, G., Cartoni, C., Ingrosso, L., Boyle, A., Galeno, R., Sbriccoli, M., Lipp, H.P., Bruce, M., Pocchiari, M., Agrimi, U. (2006). Efficient Transmission and Characterization of Creutzfeldt–Jakob Disease Strains in Bank Voles. PloS Pathog. 2, e12
  • Ladogana, A., Puopolo, M., Poleggi, A., Almonti, S., Mellina, V., Equestre, M., Pocchiari, M. (2005).High incidence of genetic human transmissible spongiform encephalopathies in Italy. Neurology, 64, 1592-1597
  • Pocchiari, M., Puopolo, M., Croes, E.A., Budka, H., Gelpi, E., Collins, S., Lewis, V., Sutcliffe, T., Guilivi, A., Delasnerie-Laupretre, N., Brandel, J.P., Alperovitch, A., Zerr, I., Poser, S., Kretzschmar, H.A., Ladogana, A., Rietvald, I., Mitrova, E., Martinez-Martin, P., de Pedro-Cuesta, J., Glatzel, M., Aguzzi, A., Cooper, S., Mackenzie, J., van Duijn C.M., Will, R.G. (2004). Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Brain, 127, 2348-2359

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