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National Veterinary Institute

National Veterinary Institute

#24 - Department of Pathology

Dr. Sylvie Benestad


Team Leader: Dr. Sylvie Benestad
Postboks 750 Sentrum
Oslo , 0106, Norway
Contact: Dr. Sylvie Benestad
Tel: +47 23 21 64 23
Fax: +47 23 21 63 03
Institute website:

Main area of research

  • Nor98/atypical scrapie, diagnosis, characterization, pathogenesis and epidemiology
  • Prion transmission barrier

Research Team Picture

Research Team

  • Researchers: 4
  • Technicians: 8
  • Postdocs: -
  • PhD/MD Students: -

Facilities and Equipment

  • Laboratories: BSL1, BSL2, BSL3
  • General equipment: Pathology, Molecular biology, Histology, Epidemiology, Risk assessment
  • Specific methods: Epidemiological methods

Main references

  • Benestad SL, Sarradin P, Thu B, Schonheit J, Tranulis MA, Bratberg B. Cases of scrapie with unusual features in Norway and designation of a new type, Nor98. Vet Rec. 2003 Aug 16;153(7):202-8.
  • Hopp P, Omer MK, Heier BT. A case-control study of scrapie Nor98 in Norwegian sheep flocks. J Gen Virol. 2006; 87: 3729-36.
  • Moum T, Olsaker I, Hopp P, Moldal T, Valheim M, Moum T, Benestad SL. Polymorphisms at codons 141 and 154 in the ovine prion protein gene are associated with scrapie Nor98 cases. J Gen Virol. 2005 Jan;86 (Pt 1):231-5.
  • Le Dur A, Beringue V, Andreoletti O, Reine F, Lai TL, Baron T, Bratberg B, Vilotte JL, Sarradin P, Benestad SL, Laude H. A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16031-6.
  • Benestad SL, Arsac JN, Goldmann W, Nöremark M. Atypical/Nor98 scrapie: properties of the agent, genetics, and epidemiology. Vet Res. 2008 Jul-Aug;39(4):19. Epub 2008 Jan 11.

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