Comenius University
#33 - Faculty of Mathematics, Physics and Computer Sciences
Contact
Team Leader: Prof. Tibor Hianik
Mlynska dolina F1
Bratislava, 84248, Slovakia
Contact: Prof. Tibor Hianik
Tel: +421 260295683
Fax: +421 265426774
E-mail: tibor.hianik@fmph.uniba.sk
Institute website:
http://www.fmph.uniba.sk/index.php?id=970
Main area of research
- Diagnostics: Development, Optimization and Validation of biosensors for detection prions in complex biological samples
Research Team
- Researchers: 3
- Technicians: 0
- Postdocs: 0
- PhD/MD Students: 2
Facilities and Equipment
- General equipments: Network analyzers, EQCM, laser ellipsometer, Langmuir-Blodgett Trough, potentiostat and electrochemical impedance analyzer, precise densitometry, ultrasound velocimetry
- Specific methods: Surface viscosity of thin layers, Electrostriction of lipid membranes, nanofabricated surfaces for biosensors.
Main references
- T. Hianik, DNA/RNA aptamers - novel recognition structures in biosensing in Electrochemical Sensor Analysis, Salvador Alegret & Arben Merkoçi (Eds.), Elsevier, pp. 801-825, 2007
- T. Hianik, V. Ostatna, Z. Zajacova, E. Stoikova, G. Evtugyn, Detection of aptamer-protein interactions using QCM and electrochemical indicator methods. Bioorg. Med. Chem. Lett. 15 (2005) 291-295
- T. Hianik, V. Ostatna, M. Sonlajtnerova, I. Grman, Influence of ionic strength, pH and aptamer configuration for binding affinity to thrombin. Bioelectrochemistry, 70 (2007) 127-133
- M. Snejdarkova, L. Svobodova, V. Polohova, T. Hianik, DNA aptamer biosensor for IgE detection using transverse shear mode method. Anal. Bioanal. Chem. 390 (2008) 1087-1091
- T. Hianik, A. Porfireva, I. Grman, G. Evtugyn, Aptabodies - new type of artificial receptors for detection proteins, Protein and Peptide Letters, in press
