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Comenius University

Comenius University

#33 - Faculty of Mathematics, Physics and Computer Sciences

Contact

Team Leader: Prof. Tibor Hianik
Mlynska dolina F1
Bratislava, 84248, Slovakia
Contact: Prof. Tibor Hianik
Tel: +421 260295683
Fax: +421 265426774
E-mail: tibor.hianik@fmph.uniba.sk
Institute website: http://www.fmph.uniba.sk/index.php?id=970

Main area of research

  • Diagnostics: Development, Optimization and Validation of biosensors for detection prions in complex biological samples

Research Team

  • Researchers: 3
  • Technicians: 0
  • Postdocs: 0
  • PhD/MD Students: 2

Facilities and Equipment

  • General equipments: Network analyzers, EQCM, laser ellipsometer, Langmuir-Blodgett Trough, potentiostat and electrochemical impedance analyzer, precise densitometry, ultrasound velocimetry
  • Specific methods: Surface viscosity of thin layers, Electrostriction of lipid membranes, nanofabricated surfaces for biosensors.

Main references

  • T. Hianik, DNA/RNA aptamers - novel recognition structures in biosensing in Electrochemical Sensor Analysis, Salvador Alegret & Arben Merkoçi (Eds.), Elsevier, pp. 801-825, 2007
  • T. Hianik, V. Ostatna, Z. Zajacova, E. Stoikova, G. Evtugyn, Detection of aptamer-protein interactions using QCM and electrochemical indicator methods. Bioorg. Med. Chem. Lett. 15 (2005) 291-295
  • T. Hianik, V. Ostatna, M. Sonlajtnerova, I. Grman, Influence of ionic strength, pH and aptamer configuration for binding affinity to thrombin. Bioelectrochemistry, 70 (2007) 127-133
  • M. Snejdarkova, L. Svobodova, V. Polohova, T. Hianik, DNA aptamer biosensor for IgE detection using transverse shear mode method. Anal. Bioanal. Chem. 390 (2008) 1087-1091
  • T. Hianik, A. Porfireva, I. Grman, G. Evtugyn, Aptabodies - new type of artificial receptors for detection proteins, Protein and Peptide Letters, in press

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